Trends in susceptibility based on the combined scaling factors of 4 major currents: INa, ICa,L, IKr, and IKs. For a given cell, current conductance scaling factors below and above the population median were labeled as low (−) and high (+) conductance, respectively. A–D: number of cells in a given subgroup with 1 of 16 combinations of high and low conductance. E–H: fraction of cells with a given high- and low-conductance combination that are in the given subpopulation.