Figure 3.

Product information. (a) Product presentation of marketed antibody-based biotherapeutics over time. Current trends show a preference of lyophilized and pre-filled syringe or pen over vial. (b) Route of administration of marketed antibody-based biotherapeutics over time. Intravenous is the most used route of administration, but recently, subcutaneous has seen a similar number of approvals as intravenous. Other routes of administration are intradermal, intramuscular, and intravitreal. (c) Regular maintenance dose frequency for marketed antibody-based biotherapeutics over time. QW stands for once weekly, Q2W stands for once every two weeks, and so on. There are 79 regular dosing regiments. In general, Q2W and Q4W are the most used maintenance dosing regimens.