. 2023 Mar 30;18(1):2196759. doi: 10.1080/15592294.2023.2196759

Table 3.

Differentially methylated regions calculated using the Comb-p method based on linear regression models. Restricted to regions overlapping between timepoints.

Hormone	CHR^a	Start^a	End^a	Genes	Location	Overlap with Transcriptional regulators	Number of CpGs
Hormone	CHR^a	Start^a	End^a	Genes	Location	Overlap with Transcriptional regulators	Total	Negative association	Positive association
DHEA	5	110062342	110062837	TMEM232	Body – Promoter	AR & ER	14	14	0
DHEA	20	44451666	44451973	TNNC2^b	3’UTR	AR & ER	5	5	0
E1	5	110062342	110062837	TMEM232	Body – Promoter	AR & ER	14	14	0
P4	17	37123637	37123949	FBXO47	Body – Promoter	AR & ER	9	0	9

Androstenedione (A), dehydroepiandrosterone (DHEA), oestrone (E1), oestradiol (E2), progesterone (P4), sex hormone binding globulin (SHBG), testosterone (T), untranslated region (UTR), Androgen Receptor (AR), Oestrogen Receptor (ESR). ^aChromosome positions refer to the Genome Reference Consortium Human Build 37 (GRCh37). ^bWithin 100k bp up/downstream of DMR.