Table 6.
Testing cascading effects of maternal pre-pregnancy BMI on infant BWz through PGH a .
| Outcome is birthweight z-score* | Full Sample (N=98) |
Black Women (N=32) |
White Women (N=66) |
|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | |
| Pre-pregnancy BMI→ PGH | -0.33 (-0.54, -0.12)** | -0.41 (-0.75, -0.08)* | -0.14 (-0.40, 0.12) |
| Pre-pregnancy BMI→ BWz | 0.16 (-0.04, 0.36) | 0.01 (-0.41, 0.43) | 0.21 (-0.01, 0.43)+ |
| PGH → BWz | 0.18 (-0.01, 0.36)+ | 0.26 (-0.19, 0.70) | 0.13 (-0.08 0.34) |
| BMI → PGH → BWz (indirect) b | -0.06 (-0.12, -0.01)+ | -0.11 (-0.31, 0.05) | -0.02 (-0.06, 0.02) |
| Pre-pregnancy BMI→ BWz (total) b | 0.10 (-0.09, 0.29) | -0.10 (-0.48, 0.28) | 0.19 (-0.02, 0.41)+ |
| Total effect model F (NDF, DDF) | 2.86 (5, 92)* | 0.96 (4, 27) | 2.78 (4, 61)* |
| Total effect model R2 | 0.13 | 0.12 | 0.15 |
a
All mediation models adjusted for maternal age at the prenatal visit, maternal education, and log-transformed IL-8. The mediation model with the full sample additionally adjusted for binary race.
b
For indirect and total effects, 95% CIs refer to the bootstrapped lower and upper confidence intervals for the effects.
+p<.10 *p <.05 **p <.01 ***p <.001.