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. 2023 Mar 31;19:693–707. doi: 10.2147/NDT.S391096

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© 2023 Chen et al.

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Patient flow diagram.

Notes: ^aOnly patients with non-response to at least 2 AD treatments prior to randomization were eligible to participate in the study. ^bTwenty-four patients entered SUSTAIN-3/TRD3008 from the double-blind treatment phase of TRD3006; 1 patient entered SUSTAIN-3/TRD3008 from the follow-up phase of TRD3006.

Abbreviations: AD, antidepressant; ESK, esketamine; TRD, treatment-resistant depression.