TE dependence of MM. Spectra measured in the human brain in vivo at 4 T at different TEs using (A) LASER sequence and (B) inversion-recovery LASER sequence (occipital lobe, volume-of-interest = 27 mL, TR = 2 s, TI = 0.67 s, 64 averages per TE). Adapted from45 with permission. (C) Spectra measured in the rat brain in vivo at 9.4 T at different TEs using SPECIAL sequence (hippocampus+cortex, volume-of-interest = 27 μL, TR = 4 s, 240 averages per TE).