Table 2. Clinical characteristics of users who received atypical antipsychotics via the Brazilian National Health System, Brazil, 2008-2017.
| Variables | Children and adolescents (up to 18 years old) | Adults (19 to 59 years old) | Older adults (60 years and older) | Total |
|---|---|---|---|---|
| N = 68,584 (%) | N = 522,071 (%) | N = 168,999 (%) | N = 759,654 (%) | |
| Principal diagnosis | ||||
| Paranoid schizophrenia | 49,847 (72.7) | 413,848 (79.3) | 126,023 (74.6) | 589,718 (77.6) |
| Hebephrenic schizophrenia | 3,462 (5.1) | 15,081 (2.9) | 3,372 (2.0) | 21,915 (2.9) |
| Catatonic schizophrenia | 306 (0.4) | 2,346 (0.4) | 674 (0.4) | 3,326 (0.4) |
| Undifferentiated schizophrenia | 2,021 (2.9) | 12,961 (2.5) | 4,093 (2.4) | 19,075 (2.5) |
| Post-schizophrenic depression | 203 (0.3) | 2,667 (0.5) | 1,198 (0.7) | 4,068 (0.5) |
| Residual schizophrenia | 858 (1.3) | 16,071 (3.1) | 5,794 (3.4) | 22,723 (3.0) |
| Simple schizophrenia | 944 (1.4) | 5,304 (1.0) | 2,021 (1.2) | 269 (1.1) |
| Other types of schizophrenia | 10,499 (15.3) | 48,758 (9.4) | 24,273 (14.4) | 83,530 (11.0) |
| Bipolar schizoaffective disorder | 202 (0.3) | 1,788 (0.3) | 629 (0.4) | 2,619 (0.3) |
| Schizoaffective disorder, depressive type | 82 (0.1) | 1,764 (0.3) | 500 (0.3) | 2,346 (0.4) |
| Schizoaffective disorder, mixed type | 160 (0.2) | 1,483 (0.3) | 422 (0.2) | 2,065 (0.3) |
| Atypical antipsychotic used when entering the pharmaceutical assistance program - CEAFa | ||||
| Clozapine | 1,518 (2.2) | 30,311 (5.8) | 2,657 (1.6) | 34,486 (4.5) |
| Olanzapine | 13,380 (19.5) | 177,787 (34.1) | 33,694 (19.9) | 224,861 (29.6) |
| Risperidone | 43,425 (63.3) | 158,415 (30.3) | 49,512 (29.3) | 251,352 (33.1) |
| Quetiapine | 8,106 (11.8) | 122,167 (23.4) | 80,139 (47.4) | 210,412 (27.7) |
| Ziprasidone | 2,155 (3.2) | 33,391 (6.4) | 2,997 (1.8) | 38,543 (5.1) |
| Users who switched the atypical antipsychotic medication at least once | ||||
| Yes | 9,242 (13.5) | 76,210 (14.6) | 14,632 (8.6) | 100,084 (13.2) |
| No | 59,342 (86.5) | 445,861 (85.4) | 154,367 (91.4) | 659,570 (86.8) |
a) CEAF: Specialized Component of Pharmaceutical Assistance/Department of Pharmaceutical Assistance, Secretariat of Science and Technology and Strategic Inputs, Ministry of Health.