Table 2.

Univariate analysis of predictors of persistent/recurrent disease.

Parameters	Long-term remission	Persistence/recurrence	χ2 or Fisher	P
No. of patients (%	414	129
Sex Male Female	135 279	56 73	5.033	0.025
Age (y) ≥55 <55	46 368	16 113	0.162	0.687
Extent of lymph node dissection Central lymph node dissection Lateral lymph node dissection Central and lateral lymph node dissection	214 12 188	33 7 89	27.257	<0.001
Number of surgeries 1 2 or moer	384 30	99 30	25.647	<0.001
Histology Classic PTC FV-PTC FTC Aggressive histology	398 8 5 3	121 1 0 7	14.215	0.003
Incomplete tumor resection Yes No	5 409	3 126	0.847	0.357
Gross ETE Yes No	54 360	33 96	11.491	0.001
BMI(kg/m2) <18.5 18.5-24 >24	42 214 148	10 73 42	1.321	0.517
Primary tumor size (cm) ≤2 >2 X	304 95 2	86 41 0	4.254	0.119
Bilaterality Yes No	129 285	48 81	1.638	0.201
Multifocality Yes No	178 236	75 54	9.065	0.003
Capsular invasion Yes No	224 190	101 28	23.948	<0.001
Invasion of loco-regional tissues or structures Yes No	83 331	50 79	18.619	<0.001
Vascular invasion Yes No	39 375	25 104	9.383	0.002
Invade nerves Yes No	26 386	15 114	3.966	0.046
T T0T1、T2 T3、T4、Tx	339 62	87 41	16.990	<0.001
N N0 N1a N1b	45 211 158	3 41 85	32.818	<0.001
ATA risk stratification Low Intermediate High	62 309 43	2 96 31	28.478	<0.001
BRAFV600E mutation of primary tumor Yes No	276 68	90 19	0.291	0.589
Number of invaded lymph nodes ≤5 >5	275 139	48 81	34.834	<0.001
Size of the largest metastatic LN(cm) ≤0.4 0.4-1.4 >1.4	260 134 20	22 65 42	114.573	<0.001
Extranodal extension of LN Yes No	123 199	76 34	31.493	<0.001
Cumulative 131I-administered activities(GBq) ≤ 7.40 > 7.40	385 29	55 74	162.279	<0.001
ps-Tg (ng/mL) ≤10.1 >10.1	324 90	36 93	111.610	<0.001

ATA, American Thyroid Association; PTC, papillary thyroid cancer; FTC, follicular thyroid cancer; FV-PTC, follicular variant PTC; ps-Tg, preablation stimulated thyroglobulin; LN, lymph node; BMI, Body Mass Index; ETE, extrathyroidal extension.