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. 2023 Mar 21;14:1094339. doi: 10.3389/fendo.2023.1094339

Table 3.

Multivariate analysis of predictors of persistent/recurrent disease.

Parameters OR(95%) P
Sex
Male
Female
1
0.993(0.531-1.858)
0.982
Extent of lymph node dissection
Central lymph node dissection
Lateral lymph node dissection
Central and lateral lymph node dissection
1
0.649(0.121-3.482)
0.582(0.175-1.935)
0.614
0.377
Number of surgeries
1
2 or more
1
1.598(0.641-3.983)
0.315
Histology
Classic PTC
FV-PTC
FTC
Aggressive histology
1
0.979(0.081-11.846)
0
6.217(0.426-90.734)
0.987
0.999
0.182
Gross ETE
Yes
No
1
0.950(0.210-4.292)
0.946
Multifocality
Yes
No
1
1.224(0.649-2.308)
0.533
Capsular invasion
Yes
No
1
1.165(0.535-2.537)
0.701
Invasion of loco-regional tissues or structures
Yes
No
1
1.501(0.679-3.319)
0.316
Vascular invasion
Yes
No
1
1.218(0.485-3.058)
0.674
T
T0、T1、T2
T3、T4、Tx
1
0.933(0.339-2.571)
0.894
N
N0
N1a
N1b
2.432(0.738-8.012) 0.144
ATA risk stratification
Low
Intermediate
High
1
3.278(0.367-29.235)
3.634(0.237-55.784)
0.288
0.354
Number of invaded lymph nodes
≤5
>5
1
0.760(0.363-1.593)
1
0.468
Size of the largest metastatic LN(cm)
≤0.4
0.4-1.4
>1.4
1
2.444(1.100-5.432)
6.614(2.204-19.850)
0.028
0.001
Extranodal extension of LN
Yes
No
1
1.280(0.660-2.485)
0.465
Cumulative 131I-administered activities(GBq)
≤7,40
>7.40
1
6.679(3.162-14.109)
<0.001
ps-Tg (ng/mL)
≤10.1
>10.1
1
4.646(2.457-8.786)
<0.001

ATA, American Thyroid Association; PTC, papillary thyroid cancer; FTC, follicular thyroid cancer; FV-PTC, follicular variant PTC; ps-Tg, pre-ablation stimulated thyroglobulin; LN, lymph node; BMI, Body Mass Index; ETE, extrathyroidal extension.