TABLE 3.
Exacerbation rates and all-cause mortality during 12-month follow-up.
| Variable | Total | Single-inhaler triple therapy (SITT) | Multiple-inhaler triple therapy (MITT) | p-value |
|---|---|---|---|---|
| N = 1328 | N = 535 | N = 793 | ||
| Exacerbations in 1 year, mean (SD) | 0(1) | 0(1) | 0(1) | 0.017 |
| Exacerbation in 1 year, n (%) | ||||
| 0 | 527 (39.7) | 356 (66.5) | 445 (56.1) | < 0.001 |
| ≥1 | 801 (60.3) | 179 (33.5) | 348 (43.9) | |
| Severe exacerbation in 1 year, n (%) | < 0.001 | |||
| Yes | 333 (25.1) | 107 (20.0) | 226 (28.5) | < 0.001 |
| No | 995 (74.9) | 428 (80.0) | 567 (71.5) | |
| Frequent exacerbation in 1 year, n (%) | 0.452 | |||
| Yes | 170 (12.8) | 64 (12.0) | 106 (13.4) | |
| No | 1158 (87.2) | 471 (88.0) | 687 (86.7) | |
| Mortality, n (%) | 50 (3.8) | 13 (2.4) | 37 (4.7) | 0.036 |