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. 2023 Apr 4;18(4):e0273202. doi: 10.1371/journal.pone.0273202

Table 4. Propensity-adjusted multiple logistic regression for risk factors associated with progression towards severe disease or death at day 14.

Population: patients with baseline suPAR ≥ 6ng/mL who fulfilled the prescriptive criteria for anakinra (n = 105)
  Variable Univariable Multivariable
OR1 95% CI1 p-value OR1 95% CI1 p-value
    Age (years) 1.07 1.04, 1.12 < 0.001 1.09 1.05, 1.14 < 0.001
    Anakinra 0.34 0.13, 0.79 0.016 0.32 0.12, 0.82 0.021
    PaO2/FiO2 ratio 1.00 0.99, 1.00 0.243 0.99 0.98, 1.00 0.051

OR: Odds Ratio; CI: Confidence Interval.

Severe disease is defined according to the WHO Clinical Progression Scale (WHO-CPS score 6–10).