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. 2023 Apr 4;3(4):e0001413. doi: 10.1371/journal.pgph.0001413

Table 1. Eligibility criteria and rationale.

No. Inclusion criteria: Rationale:
1. • English-language publications (only) • Limited access to translation services
2. • Published between December 2019 and 24 November 2022 • Timeline corresponds with first identification of SARS-CoV-2 in December 2019, in Wuhan, China
3. Country-of-origin: Any • For comprehensive appraisal of evidence on global outcomes
4. • Pre-prints (not excluded) • For comprehensive appraisal of evidence
• Evidence is emerging contemporaneously on this current global health challenge
5. Scope:
• Elective breast- or colorectal cancer surgery backlogs, attribu mortality and/or implemented health system responses during the COVID-19 pandemic
• To synthesise known findings and, identify existing gaps in the evidence base
• To address the research aims
6. Data synthesis on surgical case performance backlogs:
• Articles based on global and/or institution-level reductions in surgical activity (i.e., number of elective procedures performed) during the COVID-19 pandemic, as compared to surgical activity pre-COVID-19
• Included due to a prevalent scarcity of evidence on absolute backlogs outcomes
• Global and institution-level reductions in surgical activity would, by reasonable inference, contribute to overall case performance backlogs
No. Exclusion criteria Rationale
• Non-English language publications
(Unable to locate translated version)
• Limited access to translation services
• Unable to locate full-text article • Avoid potential bias from incomplete appraisal of study findings
• Significant methodological quality deficit • Findings insufficiently reliable
• Opinion pieces, correspondence articles (apart from research letters)
• Guidelines on operative aspects
• Protocols, posters
• Conference abstracts
• Symposium minutes
• Opinion pieces–Findings subjective
• Operative guidelines–Limited relevance to research question, specialist operative techniques fall beyond the scope of this review
• Other–Definitive, complete evidence prioritised for review
Out of scope:
• Reported on outcomes for other diagnoses (apart from breast- or colorectal cancer, in isolation)
• Small-scale review, hence approximately 1,288 articles on impact for other cancer types excluded
• Other conditions not relevant to research question
Out of scope:
• Focused on emergent surgery, without reporting on outcomes for elective surgery in isolation
• To avoid misclassification bias between outcomes for emergent surgery and those for elective surgery