Table I.
Patient and clinical characteristics of singleton pregnancies resulting from fresh donor oocyte versus autologous oocyte cycles, in women <35 years of age, USA, 2010–2015.
| Donor oocyte recipients | Autologous oocyte patients | P value | |||
|---|---|---|---|---|---|
| Characteristics N = 71 720 | N | Percent (%) | N | Percent (%) | |
| Age | |||||
| <25 | 42 | 2.0 | 1497 | 2.2 | 0.0003 |
| 25–29 | 471 | 22.4 | 18271 | 26.3 | |
| 30–34 | 1592 | 75.6 | 49 847 | 71.6 | |
| Race/ethnicity | |||||
| Non-Hispanic White | 1059 | 50.3 | 34547 | 49.6 | 0.0884 |
| Non-Hispanic Black | 50 | 2.4 | 2385 | 3.4 | |
| Asian/Pacific Islander | 159 | 7.6 | 4995 | 7.2 | |
| Hispanic | 125 | 5.9 | 3685 | 5.3 | |
| Other | * | <1 | 110 | 0.2 | |
| Missing | * | −34.0 | 23 893 | 34.3 | |
| Infertility diagnosis | |||||
| Tubal factor | 107 | 5.1 | 9687 | 13.9 | <.0001 |
| Endometriosis | 187 | 8.9 | 7990 | 11.5 | 0.0002 |
| Uterine factor | 59 | 2.8 | 2294 | 3.3 | 0.2115 |
| disorder | 153 | 7.3 | 15 084 | 21.7 | <.0001 |
| Diminished ovarian reserve | 1194 | 56.7 | 5947 | 8.5 | <.0001 |
| Male factor | 350 | 16.6 | 30 020 | 43.1 | <.0001 |
| Unexplained | 97 | 4.6 | 11 005 | 15.8 | <.0001 |
| BMI (kg/m 2 ) | |||||
| <18.5 | 59 | 2.8 | 1846 | 2.7 | <.0001 |
| 18.5–24.9 | 953 | 45.3 | 33 374 | 47.9 | |
| 25.0–29.9 | 364 | 17.3 | 13 166 | 18.9 | |
| ≥30 | 254 | 12.1 | 9641 | 13.9 | |
| Missing | 475 | 22.6 | 11 588 | 16.7 | |
| Number of prior pregnancies | |||||
| 0 | 1188 | 57.8 | 39 331 | 56.7 | <.0001 |
| 1 | 412 | 20.0 | 17288 | 24.9 | |
| ≥2 | 456 | 22.2 | 12 803 | 18.4 | |
| Number of prior spontaneous abortions | |||||
| 0 | 1597 | 78.0 | 54 356 | 78.5 | <.0001 |
| 1 | 268 | 13.1 | 10591 | 15.3 | |
| ≥2 | 183 | 8.9 | 4342 | 6.3 | |
| Number of prior preterm births | |||||
| 0 | 2001 | 97.9 | 67 305 | 97.3 | 0.105 |
| ≥1 | 43 | 2.1 | 1861 | 2.7 | |
| Number of prior term births | |||||
| 0 | 1668 | 81.3 | 55 601 | 80.2 | <.0001 |
| 1 | 250 | 12.2 | 11 033 | 15.9 | |
| ≥2 | 134 | 6.5 | 2682 | 3.9 | |
| Number of prior ART cycles | |||||
| 0 | 1023 | 48.6 | 49 503 | 71.2 | <.0001 |
| 1 | 368 | 17.5 | 10 638 | 15.3 | |
| ≥2 | 712 | 33.9 | 9418 | 13.5 | |
| Use of ICSI | |||||
| Yes | 1653 | 78.5 | 53 466 | 76.9 | 0.0848 |
| No | 452 | 21.5 | 16041 | 23.1 | |
| Use of assisted hatching | |||||
| Yes | 390 | 18.5 | 16981 | 24.4 | <.0001 |
| No | 1715 | 81.5 | 52 634 | 75.6 | |
| Embryo stage at transfer | |||||
| Day 2/3 | 357 | 17.0 | 21 695 | 31.2 | <.0001 |
| Day 5/6 | 1714 | 81.4 | 46 747 | 67.2 | |
| Other | 34 | 1.6 | 1173 | 1.7 | |
| Number of embryos transferred | |||||
| 1 | 763 | 36.3 | 24229 | 34.8 | <.0001 |
| 2 | 1269 | 60.3 | 41 028 | 58.9 | |
| ≥3 | 73 | 3.5 | 4358 | 6.3 | |
| Number of supernumerary embryos cryopreserved | |||||
| 0 | 431 | 20.6 | 25 381 | 36.6 | <.0001 |
| 1 to 2 | 435 | 20.7 | 16 192 | 23.3 | |
| 3 to 4 | 431 | 20.6 | 12 385 | 17.9 | |
| ≥5 | 800 | 38.2 | 15 427 | 22.2 | |
| Elective single embryo transfer | |||||
| Yes | 699 | 34.3 | 19 198 | 29.7 | <.0001 |
| No | 1342 | 65.8 | 45 386 | 70.3 | |
| Cycle resulted in live birth? | |||||
| Yes | 1883 | 89.5 | 62 071 | 89.2 | 0.6727 |
| No | 222 | 10.6 | 7544 | 10.8 | |
*
Data suppressed due to cell count <5