Table 3.

Standardized Incidence Ratios for Acute CVE in Transgender Individuals With GAHT Compared With a Reference Cohort²⁰

Event	No. events	Incidence rate (/100,000 person-years)	Expected no. events	Standardized incidence ratio (95% CI)	Expected no. events	Standardized incidence ratio (95% CI)
Transgender women with GAHT (n=2,517)			Reference: cisgender women		Reference: cisgender men
VTE	73	320	13.22	5.52 (4.36–6.90)*	16.04	4.55 (3.59–5.69)*
Stroke	29	127	12.01	2.42 (1.65–3.42)*	16.08	1.80 (1.23–2.56)*
MI	30	131	11.38	2.64 (1.81–3.72)*	38.03	0.79 (0.54–1.11)
Transgender men with androgens (n=1,358)			Reference: cisgender men		Reference: cisgender women
VTE	2	18	5.56	0.36 (0.06–1.19)	4.84	0.41 (0.07–1.37)
Stroke	6	55	4.10	1.46 (0.59–3.04)	3.49	1.72 (0.70–3.58)
MI	11	100	10.99	1.00 (0.53–1.74)	2.98	3.69 (1.94–6.42)*

Reproduce with permission from Nota NM, et al.²⁰ *Significant finding. Abbreviations as in Table 2.