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. 2023 Mar 1;55(3):520–531. doi: 10.1038/s12276-023-00947-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A Notch-1 and Hes-1 protein expression in iWAT obtained from ND- and HFD-fed WT mice. B, C Protein and mRNA expression of the indicated genes in iWAT obtained from the HFD-fed WT and KO mice. D-E The 3T3-L1 adipocyte line was treated with SHAM1 (Notch-1 inhibitor) in the presence or absence of recombinant TGFBI. F Localization of Notch-1 in 3T3-L1 cells treated with either recombinant TGFBI or galectin-3. G Indicated protein expression in the cytoplasm (left) and nucleus (right).