Table 4.

Application of the proposed method for the determination of the drugs in dosage forms.

Parameter	Proposed method			Comparison method65
	Conc.taken (μM)	Conc.found (μM)	% recoverya	% recoverya
RFP
REP capsules (300 mg/capsule)	5.0	5.09	101.91	101.19
	10.0	9.89	98.87	97.9
	15.0	14.90	99.36	97.8
Mean			100.05	98.96
± SD			1.63	1.93
% RSD			1.628	1.949
Student t-test	0.74 (2.77)b
Variance ratio F-value	1.39 (19.0)b

Parameter	Proposed method			Comparison method14
	Conc.taken (μM)	Conc.found (μM)	% recoverya	% recoverya
TNZ
Protozole® coated tablets (TNZ, 500 mg/tablet)	50.0	49.57	99.14	97.7
	100.0	101.67	101.67	97.39
	150.0	147.71	98.47	95.19
Mean			99.76	96.76
± SD			1.69	1.37
% RSD			1.691	1.412
Student t-test	2.39 (2.77)b
Variance ratio F-value	1.52 (19.0)b

Parameter	Proposed method			Comparison method13
	Conc.taken (μM)	Conc.found (μM)	% recoverya	% recoverya
ONZ
Astranida® coated tablets (ONZ, 500 mg/tablet)	25.0	24.66	98.64	98.9
	50.0	48.64	97.80	101.14
	75.0	76.02	101.36	102.08
Mean			99.27	100.71
± SD			1.86	1.63
% RSD			1.875	1.623
Student t-test	1.01 (2.78)b
Variance ratio F-value	1.29 (19.0)b

Parameter	Proposed method			Comparison method12
	Conc.taken (μM)	Conc.found (μM)	% recoverya	% recoverya
MNZ
Flagyl® coated tablets (MNZ, 500 mg/tablet)	10.0	9.95	99.48	98.2
	25.0	24.83	99.31	98.9
	40.0	39.81	99.53	99.1
Mean			99.44	98.73
± SD			0.12	0.47
% RSD			0.116	0.479
Student t-test	2.52 (2.78)b
Variance ratio F-value	16.79 (19.0)b

^aMean of three determinations.

^bValues in parenthesis are the tabulated t- and F-values at p = 0.05⁶⁴.