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. 2023 Apr 4;13:5511. doi: 10.1038/s41598-023-32710-5

Table 2.

Summary of the effects of selected fatty acids on the productions of TNF, IL-1β, and IL-6 in the THP-1 monocytes cultured with and without LPS treatment.

Fatty acid without LPS with LPS
TNF IL-1β IL-6 TNF IL-1β IL-6
caprylic acid N/A N/A N/A
capric acid N/A N/A N/A
undecylic acid N/A N/A N/A
lauric acid N/A N/A N/A
palmitic acid N/A N/A N/A
stearic acid N/A N/A N/A
palmitoleic acid /a / /
oleic acid / / /
linoleic acid / /― /
α-linolenic acid / /― /
γ-linolenic acid /― / /
arachidonic acid / /― /
EPA / / /
DPA / / /
DHA / / /

: increase; ↓: decrease; ―: unchanged; a: trend at low concentration/trend at high concentration of FAs.