Table 3.
Comparison of sensitivity and specificity of OUD algorithm and ICD codes from the main analysis to that from the sensitivity analyses
| Main analyses | Exclude iteration 1 | OUD only where both reviewers agreea | OUD only if at least four DSM criteria were met | ||
|---|---|---|---|---|---|
| Stage 3 | Se (95% CI) | 23.04% (22.64-23.44) | 24.60% (24.08-25.12) | 25.12% (24.58-25.66) | 26.90% (26.39-27.51) |
| Sp (95% CI) | 98.36% (98.32-98.40) | 98.64% (98.60-98.69) | 97.51% (97.47-97.56) | 97.35% (97.30-97.40) | |
| ICD at stage 3 | Se (95% CI) | 10.34% (10.10-10.59) | 12.24% (11.92-12.55) | 11.75% (11.44-12.06) | 17.09% (16.65-17.53) |
| Sp (95% CI) | 99.54% (99.52-99.57) | 99.64% (99.62-99.67) | 99.17% (99.14-99.21) | 99.21% (99.18-99.24) | |
| Stage 4 | Se (95% CI) | 16.37% (16.03-16.71) | 17.13% (16.70-17.55) | 14.41% (14.00-14.82) | 15.53% (15.07-15.99) |
| Sp (95% CI) | 98.55% (98.51-98.59) | 98.74% (98.70-98.78) | 97.73% (97.68-97.78) | 97.67% (97.63-97.72) | |
| ICD at stage 4 | Se (95% CI) | 10.11% (9.86-10.37) | 11.35% (11.04-11.66) | 12.07% (11.73-12.41) | 15.67% (15.24-16.11) |
| Sp (95% CI) | 99.66% (99.64-99.68) | 99.63% (99.60-99.65) | 99.33% (99.30-99.36) | 99.35% (99.32-99.37) |
Abbreviations: Se – sensitivity; Sp – specificity; OUD – opioid use disorder; ICD – international classification of diseases; DSM – Diagnostic and Statistical Manual of Mental Disorders.
a
– This applies only to cases where two reviewers reviewed a case – if both reviewers considered the case to be OUD then the case was considered to be OUD; if one reviewer considered the case to be OUD and another didn’t, OR both reviewers considered the case to be non-OUD, then the case was considered to be non-OUD; if only one reviewer reviewed the case, then that reviewer’s adjudication was considered as it is.