Table 2.

Association of LDL cholesterol ≥193 mg/dL vs <116 mg/dL with development of myocardial infarction and ASCVD, stratified by CAC groups in the Western Denmark Heart Registry

		Myocardial infarction		ASCVD
Atherosclerosis measurement	N (%)	N (%)	Adjusted* Hazard ratio	N (%)	Adjusted* Hazard ratio
Overall	11,805	131	3.12 (1.96–4.98)	286	2.10 (1.45–3.03)
CAC = 0	6,366	35 (0.5)	0.95 (0.33–2.73)	94	0.92 (0.48–1.79)
CAC > 0	5,439	96 (1.8)	3.53 (2.11–5.92)	192	2.42 (1.59–3.67)

^*Adjusted for age, sex, smoking status, diabetes, hypertension, level of comorbidity based on Charlson Comorbidity Index score (0 = low, 1= moderate and ≥2severe), post-CTA statin use, HDL-cholesterol and LDL-C. ASCVD=atherosclerotic cardiovascular disease, CAC=coronary artery calcium, LDL=low-density lipoprotein.