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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Andrology. 2023 Feb 14;11(4):698–709. doi: 10.1111/andr.13400

Figure 3. Ablation of ADAD2 causes dramatic transcriptomic changes in the male germline.

Figure 3.

(A) An MA plot depicting differentially expressed genes in the testes from wildtype and Adad2Δ/Δ male mice at 24 days postpartum. Each dot represents one gene; the x-axis and y-axis denotes the log2 value of mean expression level and fold change, respectively. Black, red, and blue indicates no significant difference, significant upregulation, and significant downregulation (more than 2-fold change), respectively. (B) RT-PCR analyses of Prm2, Stambp, and Tex101 in the spermatocytes (Sc) and spermatids (St) from Adad2+/Δ and Adad2Δ/Δ male mice. Gapdh was analyzed in parallel as a loading control. (C – D) RT-qPCR analyses of Stambp and Tex101 in the spermatocytes (Sc) and spermatids (St) from Adad2+/Δ and Adad2Δ/Δ male mice.