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. 2023 Mar 22;13:1073311. doi: 10.3389/fonc.2023.1073311

Table 2.

List of primers used in this study.

Characteristic Total cohortN (Percentage) Resectable* Borderline resectable * Unresectable* P value
Total Number of patients 375 242 88 45
Median Age 55 (range: 22-82). 53 (22-78) 57 (26-82) 53(24-81) 0.49
Male : Female 1.8:1 1.8:1 2.3:1 2.2:1
Primary Site
Right colon and Transverse colon
Decending colon
Sigmoid colon
Rectum
98 (26.13%)
7 (1.86%)
49(13.06%)
221(58.5%)
_ _
Treatment groups
Surgery
Non Surgery
217 (57.86%)
158 (42.13%)
165(68.18%)
77 (31.81%)
51 (57.95%)
37 (42.04%)
1 (2.2%)
44 (97.77%)
T Stage
T1
T2
T3
T4
Tx
42 (11.20%)
53 (14.13%)
221(58.93%)
55 (14.66%)
4 (1.06%)
22 (9.09%)
32(13.32%)
150(61.98%)
36 (14.87%)
2 (0.8%)
11 (12.5%)
12 (13.63%)
51 (57.95%)
14 (15.90%)
0
9 (2%)
9 (2%)
20 (44.44%)
5 (11.11%)
2 (4.44%)
0.086
Nodal stage
N0
N1
N2
Nx
109 (29.03%)
231 (61.6%)
31 (8.26%)
4 (1.06%)
69 (28.51%)
147(60.74%)
24 (9.91%)
2 (0.8%)
24 (27.27%)
60 (68.18%)
4 (4.5%)
0
16 (35.55%)
24 (53.33%)
3 (6.66 %)
2 (4.44%)
0.116
kRAS Mutation
Wild Type
Not Tested
97 (25.86 %)
200(53.30%)
78 (20.8%)
60 (24.79%)
119(49.17%)
63 (26.03%)
25 (28.40%)
50 (56.81%)
13 (14.77%)
12 (26.66%)
31 (68.88%)
2 (4.44%)
Multiple liver metastasis (more than 1) 205 84 (34.71%) 77 (87.5%) 44 (97.7%) 0.01
Number of liver lesions ≥ 4 64 2 (0.8%) 35 (39.77%) 27(60%) <0.01
Mean Size (Cumulative) of lesions 3.58cm ±2.19 3.31 cm ±2.23 4.01 ±2.55 5.6cm ±1.8 0.01
Size of lesion >5 cm 70 5 (2.06%) 26 (29.54%) 39 (86.66%) <0.01
Distribution
Unilobar
Bilobar
258
117
227 (93.80%)
15 (6.19%)
31 (35.22%)
57 (64.77%)
0
45 (100%)
<0.01
Neoadjuvant Chemotherapy 237 104 (42.97%) 88 (100%) 45 (100%) <0.0001
Simultaneous Resections 60 /224 (27.67 %) 60(23.96%) 0 0
Synchronous
Metachronus
247
128
143 (59.09%)
99 (40.90%)
68 (77.27%)
20 (22.72%)
36 (80%)
9 (20%)
0.001
Median CEA 56 (IQR 2-112 ) 11.5 IQR (4-42.8) 14 (IQR :6.8-69.74) 77(IQR 11-56) 0.8

CEA, carcinoembryonic antigen.