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. 2023 Mar 22;11:1155052. doi: 10.3389/fbioe.2023.1155052

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Copyright © 2023 Hong, Zhao, Li, Yang, Chen, Wang, Luo and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative hallmarks for characterizing the mature SC-CM. Cav1.2, L-type Ca²⁺ channel; CM, cardiomyocyte; Cx43, connexin43; HIF-1α, hypoxia inducible factor 1α; hPSC, human pluripotent stem cell; NCX, Na⁺/Ca²⁺ exchanger; PPAR, peroxisome proliferator-activated receptor; RyR, ryanodine receptor; SR, sarcoplasmic reticulum.