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. 2023 Mar 22;14:1119103. doi: 10.3389/fphar.2023.1119103

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Copyright © 2023 Peng, Zong, Zhao, Shi, Lu, Qu, Han, Zhao, Jia and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PEW reduces mRNA expression of Th1 and Th17 cytokines and nuclear transcript factors (IFN-γ, T-bet, IL-17, and ROR-rt) in DNCB-induced mice skin lesions. (A–H). Relative mRNA expression levels of different nuclear transcript factors and cytokines (n = 5/group): (A) T-bet, (B) GATA-3, (C) ROR-rt, (D) AHR, (E) IFN-γ, (F) IL-4, (G) IL-17A, and (H) IL-22. The data were presented as means ± SD. # p < 0.05, ## p < 0.01, ### p < 0.001 VS. the normal group; * p < 0.05, ** p < 0.01 VS. the model control group.