Table 2.

Summary of DNA methyltransferases whose structure has been determined.

Site	Name	Target sequence	Type	Ref
m6A	M.BthVORF4518P	Unknown	I	Park et al. (2012)
	M.VvuYORF266P
	M.Sth18311ORF711P
	M.MmaGORF429P
	DpnM	5′-GATC-3′		Tran et al. (1998)
	M.EcoKI	5′-AACNNNNNGTGC-3′		Kennaway et al. (2009)
	M.EcoR124I	5′-GAANNNNNRTCG-3′		Taylor et al. (2012)
	M.TteMI	5′-CACNNNNNNNTGC-3′		Liu et al. (2017)
	LlaBIII*	5′-GGCTNA-3′		Kulkarni et al. (2016)
	LlaGI*	5′-CRTCNAG-3′
	M1.HpyAVI	5′-GAGG-3′	II	Ma et al. (2016)
	BpuSI	5′-GGGAC-3′		Shen et al. (2011)
	M.MboIIA	5′-GAAGA-3′		Osipiuk et al. (2003)
	MmeI	5′-TCCRAC-3′		Callahan et al. (2016)
	M.RsrI	5′-GAATTC-3′		Scavetta et al. (2000)
	M.TaqI	5′-TCGA-3′		Goedecke et al. (2001)
	Dam	5′-GATC-3′	Orphan methyltransferase	Horton et al. (2015)
	CcrM	5′-GANTC-3′		Horton et al. (2019)
	M.HpyAXI	5′-GCAG-3′	III	Narayanan et al. (2020)
	Ecop15I	5′-CAGCAG-3′		Gupta et al. (2015)
m5C	M.EcoKO157ORF1953P	Unknown	II
	M.HaeIII	5′-GGCC-3′		Reinisch et al. (1995)
	M.HhaI	5′-GCGC-3′		Cheng et al. (1993)
	M.MpeI	5′-CG-3′	Orphan methyltransferase	Albert et al. (2018)
	M.SflTDcmP	Unknown
m4C	M.PvuII*	5′-CAGCTG-3′	II	Gong et al. (1997)
	TTHA0409	Unknown		Morita et al. (2008)