Table 2.

Results of GGT, CRT and ICT in the two group before and after treatment.

Characteristic		Normal values	Treatment (n=18)		Placebo (n=19)
			Baseline	Post-treatment	Baseline	Post-treatment
Glucose (mmol/L)	Fasting	3.90-6.10	5.67 ± 0.8	5.50 ± 0.68	5.58 ± 0.81	5.53 ± 0.77
	30 min.	7.78-8.89	9.55 ±1.29	8.98 ± 1.13***	8.82 ± 1.47	8.58 ± 1.45*
	60 min.	7.78-8.89	9.47 ± 2.87	8.96 ± 2.53*	8.32 ± 2.99	8.55 ± 2.91
	120 min.	3.90-7.80	7.09 ± 1.59	6.60 ± 1.9**	7.18 ± 2.21	7.03 ± 2.03
	180 min.	3.90-6.10	5.2 ± 1.73	4.89 ± 1.38*	5.00 ± 1.17	5.38 ± 1.35
	AUC		1379 ± 135.8	1298 ± 130.6	1317 ± 151.7	1324 ± 145.2
C-peptide (ng/mL)	Fasting	0.52--4.38	3.72 ± 1.27	3.22 ± 0.86*	3.96 ± 1.37	3.86 ± 1.29
	30 min.	3.58--13.2	11.16 ± 4.48	9.89 ± 3.68**	9.5 ± 3.37	9.86 ± 3.7
	60 min.	3.58--13.2	12.49 ± 4.05	11.13 ± 2.48*	10.02 ± 2.74	11.24 ± 2.76
	120 min.	1.2--11.3	10.66 ± 3.63	9.46 ± 2.68**	10.24 ± 3.13	10.22 ± 2.54
	180 min.	0.38--6.56	6.34 ± 2.76	6.05 ± 2.28*	6.08 ± 2.6	6.75 ± 2.76
	AUC		1783 ± 248.6	1595 ± 188.4	1676 ± 188.2	1592 ± 199.4
Insulin (μU/mL)	Fasting	2.3--26.0	21.44 ± 11.01	17.57 ± 7.689*	24.09 ± 14.19	21.99 ± 12.26
	30 min.	10.5--61.8	170.33 ± 125.32	126.39 ± 72.06**	120.6 ± 84.15	108.66 ± 74.98*
	60 min.	10.5--61.8	155.62 ± 95.62	92.31 ± 55.29***	104.76 ± 57.01	122.09 ± 62.14
	120 min.	1.02-- 41.09	112.34 ± 74.74	71.06 ± 39.55**	104.08 ± 63.73	88.59 ± 43.48
	180 min.	0.25-- 11.53	41.55 ± 33.24	32.03 ± 23.13*	34.98 ± 35.88	40.85 ± 40.40
	AUC		20422 ± 5487	13684 ± 3112	15999 ± 3583	15863 ± 4092

Data are shown as mean ± SD. Intra-group analyses were performed by using t test followed by Wilcoxon by Prism 9 software, p value, **< 0.01, ***< 0.001. GTT, Glucose tolerance test; CPRT, C-peptide release test; IRT, Insulin release test; F.B.S, Fasting blood sugar.