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. 2023 Mar 22;14:1052925. doi: 10.3389/fimmu.2023.1052925

Figure 5.

Figure 5

Increased H3K4me3 and H3K4me1 deposition in MitoPark mice and postmortem human PD brains. (A) Representative Western blots and (B, C) densitometry assessing H3K4me1 and H3K4me3 deposition in the substantia nigra (SN) of MitoPark mice (n=4). Representative Western blots and densitometry assessing (D, E) H3K4me3 and (F, G) H3K4me1 deposition in the SN of postmortem human PD brains (n=4). LC, littermate controls; MP, MitoParks; PD, human PD patients; ND, non-disease subjects. Data show mean ± SEM of one-way ANOVA followed by Tukey’s post hoc test. Ctrl, control; ns, not significant; *p ≤ 0.05; ***p<0.001.