TABLE 3.
Prevalence of MCMs in the two groups.
| MCMs | Women with MgO prescriptions in the first trimester (n = 9,852) | Women with KRR prescriptions in the first trimester (n = 450) | ||
|---|---|---|---|---|
| N | % | N | % | |
| MCMs overall | 680 | 6.9 | 28 | 6.2 |
| MCMs of the nervous system | 43 | 0.4 | 2 | 0.4 |
| MCMs of the eyes, ears, face, and neck | 13 | 0.1 | 0 | 0 |
| MCMs of the circulatory system | 248 | 2.5 | 13 | 2.9 |
| MCMs of the respiratory system | 34 | 0.3 | 2 | 0.4 |
| Cleft lip and cleft palate | 15 | 0.2 | 0 | 0 |
| MCMs of the digestive system | 47 | 0.5 | 3 | 0.7 |
| MCMs of the genital organs | 44 | 0.4 | 0 | 0 |
| MCMs of the urinary system | 48 | 0.5 | 3 | 0.7 |
| MCMs and deformations of the musculoskeletal system | 216 | 2.2 | 6 | 1.3 |
| Other MCMs | 27 | 0.3 | 2 | 0.4 |
Abbreviations: MgO = magnesium oxide; MCM, major congenital malformation; KRR, Kampo-containing rhubarb rhizome.