. 2023 Mar 22;10:1139967. doi: 10.3389/fcvm.2023.1139967

Table 2.

Hazard ratios for the association between iCEBc and All-cause death and cardiac death.

Death	iCEBc^a	Model 1^b		Model 2^c		Model 3^d		Model 4^e
Death	iCEBc^a	HR (95% CI)	P-value	HR (95% CI)	P-value	HR (95% CI)	P-value	HR (95% CI)	P-value
All-cause	Per-SD increase	1.06 (0.98–1.15)	0.127	1.18 (1.09–1.29)	<0.001	1.13 (1.04–1.23)	0.003	1.61 (1.30–2.01)	<0.001
	Normal iCEBc	1.00 (reference)		1.00 (reference)		1.00 (reference)		1.00 (reference)
	Prolonged iCEBc^f	1.36 (1.24–1.49)	<0.001	1.32 (1.20–1.45)	<0.001	1.24 (1.13–1.36)	<0.001	1.25 (1.11–1.42)	<0.001
Cardiac	Per-SD increase	1.06 (0.91–1.24)	0.456	1.24 (1.05–1.47)	0.013	1.19 (1.01–1.41)	0.038	1.85 (1.20–2.87)	0.006
	Normal iCEBc	1.00 (reference)		1.00 (reference)		1.00 (reference)		1.00 (reference)
	Prolonged iCEBc	1.44 (1.19–1.73)	<0.001	1.41 (1.17–1.70)	<0.001	1.33 (1.10–1.61)	0.003	1.34 (1.04–1.71)	0.022

^{^a}

iCEBc, index of cardiac electrophysiological balance with heart rate correction.

^{^b}

Model 1: unadjusted model.

^{^c}

Model 2: adjusted for age, sex, race/ethnicity, income, body mass index.

^{^d}

Model 3: Model 2 additionally adjusted for smoke, myocardial infarction, stroke, congestive heart failure, diabetes mellitus, family history of cardiovascular disease, antihypertensive medications use, HDL cholesterol, total cholesterol, diastolic blood pressure, systolic blood pressure, serum potassium, serum calcium.

^{^e}

Model 4: Model 3 additionally adjusted for QRS duration, corrected QT interval and RR interval.

^{^f}

Prolonged iCEBc: male ≥4.57, female ≥4.98.