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. 2023 Feb 9;46:101148. doi: 10.1016/j.gore.2023.101148

Table 1.

Recommended eye mitigation strategies.

Drug Eye Exam Lubricating eye drops Corticosteroid eye dropsa Vasoconstrictor eye dropsb Cold Packs Contact lenses
Tisotumab Baseline and prior to each cycle Daily and as needed and for 30 days after last infusion 1 drop each eye tid- 1st about 10 min prior to infusion D1-3 3 drops per eye immediately prior to infusion or as prescribed Cover eyes with cold packs for 60 min- start prior to infusion, continue about 20 min after infusion complete Avoid use
Mirvetuximab Baseline and every other cycle for first 8 cycles At least qid (wait 10 min after applying steroid drop) 1 drop each eye 6 times/day −1 to Day 4, 1 drop each eye qid D5-8 Not recommended Not recommended Avoid use

aFor example dexamethasone 0.1%.

bFor example brimonidine 0.2%.