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. 2023 Mar 22;14:1122125. doi: 10.3389/fendo.2023.1122125

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Copyright © 2023 Matsuno, Yokoe, Nagatsuka, Morihara, Moriwaki and Asahi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Restoration of cardiac dysfunction and enlargement by the treatment of TDZD-8 in WT and Ogt-Tg mice after TAC4W. Echocardiographic analysis of (A) Ejection fraction (EF), (B) Fractional shortening (FS), (C) left ventricular (LV) end-diastolic dimension (LVIDd), (D)end-systolic LV internal dimension (LVIDs) in TAC4W-treated WT and Ogt-Tg mice. The data were evaluated by two-way analysis of variance (ANOVA) followed by Tukey’s test. Values are shown as mean ± SD (n=4). *P<0.05. TAC, transverse aortic constriction.