Table 3.

Univariate and multivariate analyses of BCa patients in the KVGH cohort

Variables	Univariate analysis				Multivariate analysis
	OS		DFS		OS		DFS
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P alue
Age
<50 years	1		1		1		1
≥50 years	1.60 (1.15–2.22)	0.005	1.31 (0.75–2.78)	0.349	1.70 (1.20–2.41)	0.003	1.26 (0.87–1.83)	0.226
Tumour T status
T1 + T2	1		1		1		1
T3 + T4	2.58 (1.67–4.00)	<0.001	2.03 (1.14–3.60)	0.015	1.40 (0.86–2.29)	0.172	0.99 (0.56–1.74)	0.974
Lymph node metastasis
No	1		1		1		1
Yes	2.42 (1.70–3.45)	<0.001	1.93 (1.10–3.38)	0.023	1.40 (0.88–2.24)	0.195	2.02 (1.18–3.45)	0.010
AJCC stage
I + II	1		1		1		1
III + IV	2.65 (1.92–3.66)	<0.001	1.55 (0.89–2.71)	0.121	2.09 (1.33–3.29)	0.001	2.30 (1.43–3.70)	0.001
ER status
Negative (0–10%)	1		1		1		1
Positive (>10%)	0.64 (0.46–0.89)	0.007	1.68 (0.95–2.99)	0.077	0.64 (0.37–1.10)	0.103	0.56 (0.29–1.08)	0.083
PR status
Negative (0–10%)	1		1		1		1
Positive (>10%)	0.75 (0.54–1.04)	0.081	1.31 (0.73–2.34)	0.362	1.32 (0.77–2.27)	0.308	1.50 (0.79–2.87)	0.219
HER2 status
0–2+	1		1		1		1
3+	1.53 (1.07–2.18)	0.019	2.66 (1.39–5.10)	0.003	1.12 (0.75–1.66)	0.579	1.05 (0.68–1.63)	0.824
F11R
Low	1		1		1		1
High	1.96 (1.42–2.70)	<0.001	2.66 (1.39–5.10)	0.003	1.92 (1.37–2.68)	<0.001	1.39 (0.95–2.02)	0.089

AJCC, American Joint Committee on Cancer, eighth edition.