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. 2023 Feb 27;26(4):106285. doi: 10.1016/j.isci.2023.106285

Figure 6.

Figure 6

The effect of glutamate treatment on mature TF-induced iPSC neurons

The cells have been treated with 100 μM glutamate for 10 min before immunostaining. The images in the bottom row display magnified views of the dendrites in the red squares. The 0 μM glutamate control neurons display drebrin clusters along the sides of the dendrite. Glutamate treatment induces the drebrin exodus from the spines, such that the dendritic shafts appear homogeneously stained in green. Cell cultures similar to those of the RNA-Seq analysis and the first ICC at day 73 have been used. White scale bar: 100 μm. Yellow scale bar in magnified dendrite images: 10 μm.