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PICO criteria
| Description | |
|---|---|
| Patient | Osteosarcopenia or osteoporosis patients |
| Intervention | Denosumab |
| Comparator | Placebo/other drugs such as zoledronic/bisphosphonate/alendronate |
| Outcome | Changes in lumbar spine BMD, handgrip strength, gait speed, appendicular lean mass, and femoral neck BMD |
BMD, bone mineral density.
