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. 2023 Feb 1;24(4):e55362. doi: 10.15252/embr.202255362

Figure EV3. NuRD knockdown larval brain phenotypes.

Figure EV3

  1. GO analysis of downregulated genes.
  2. Mi‐2 knockdown does not affect NSC numbers in the VNC. (B) Example images from ventral and dorsal sections of the VNC. Scale bars = 20 μm.
  3. Quantification of Dpn‐positive cells (no significant difference). Six VNCs measured for each genotype. No significant difference (two‐tailed student's t‐test). Represented as a box plot.
  4. MTA1‐like knockdown causes an optic lobe phenotype. (D) Representative images of control (elav‐GAL4;; mCherry RNAi), and MTA1‐like knockdown in the third instar larval CNS (all scale bars = 20 μm). Discs large (Dlg) = green, Deadpan (Dpn) = magenta. Neuroepithelial cells are highlighted by dashed lines.
  5. Quantification of optic lobe neuroepithelial cells of genotypes shown in panel A. At least eight brains measured for each genotype. ***P < 0.001 (one‐tailed student's t‐test). Represented as a box plot.