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. 2023 Feb 21;24(4):e56524. doi: 10.15252/embr.202256524

Figure EV2. PeSC signature in human cancer single‐cell data.

Figure EV2

  • A, B
    Application of ovarian cancer pericyte (A) and brain cancer pericyte score (B) to our mouse single‐cell RNAseq analysis showing enrichment in the unique cluster of PeSC.
  • C
    Pooled single‐cell RNAseq data to UMAP analysis from 35 samples (11 normal pancreas and 24 PDAC patients), including a total number of over 80,000 cells. The UMAP shows the distribution of each cell cluster.
  • D
    Cell types of each cluster were identified based on Muraro's single‐cell dataset as a reference.
  • E, F
    Unsupervised clustering UMAP analysis distinguishes 23 subclusters in the integration of whole 35 samples (E), pooled from 11 normal pancreas samples and 24 PDAC samples (F).