Table 1. Demographic and Clinical Characteristics of Dallas Heart Study Participants.
| Characteristics | Participants, No. (%) | P valueb | ||
|---|---|---|---|---|
| All DHS participants (n = 2427) | Any aPL positivea (n = 353) | All aPL negative (n = 2074) | ||
| Demographics | ||||
| Age, mean (SD), y | 50.6 (10.3) | 53.6 (10.3) | 50.4 (10.3) | NA |
| Sex | ||||
| Female | 1399 (57.6) | 222 (62.9) | 1177 (56.8) | .03 |
| Male | 1028 (42.4) | 131 (37.1) | 897 (43.2) | .19 |
| Race and ethnicity | ||||
| Black | 1244 (51.3) | 198 (56.1) | 1046 (50.4) | .05 |
| Hispanic | 339 (14.0) | 51 (14.4) | 288 (13.8) | .78 |
| White | 796 (32.8) | 102 (28.9) | 694 (33.5) | .09 |
| Otherc | 48 (2.0) | 2 (0.6) | 46 (2.2) | .05 |
| Other cardiovascular risks | ||||
| BMI, mean (SD) | 31.2 (7.5) | 32.0 (7.6) | 31.1 (7.4) | .02 |
| BP, mean (SD), mm Hg | ||||
| Systolic | 133 (20) | 135 (22) | 132 (20) | .03 |
| Diastolic | 81 (9) | 81 (10) | 81 (9) | .33 |
| HbA1c, mean (SD), % | 5.7 (1.1) | 5.8 (1.2) | 5.8 (1.1) | .52 |
| LDL cholesterol, mean (SD), mg/dL | 115 (36) | 112 (35) | 116 (36) | .05 |
| HDL cholesterol, mean (SD), mg/dL | 52 (15) | 52 (15) | 52 (15) | .91 |
| Triglycerides, mean (SD), mg/dL | 125 (86) | 126 (82) | 125 (87) | .18 |
| Current smoker | 532 (22.0) | 77 (21.8) | 455 (22.0) | .97 |
Abbreviations: aPL, antiphospholipid antibodies; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); BP, blood pressure; DHS, Dallas Heart Study; HbA1C, hemoglobin A1C; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
SI conversion factors: To convert cholesterol to millimoles per liter, multiply by 0.0259; triglycerides to millimoles per liter, multiply by 0.0113.
a
Based on the manufacturer’s cutoff.
b
Compared demographic and clinical characteristics between participants who were aPL-positive and participants who were aPL-negative.
c
Included Asian or Pacific Islander, American Indian or Alaska Native, and other self-reported race and ethnicity by Dallas Heart Study participants.