Table 2:

Clinical Outcomes in Xylazine vs. Control Patients

Clinical Outcome Variables	Xylazine (N=90)	Control (N=231)	P-Value
Cardiovascular (CV) Outcomes
Received CPR	4 (4.4%)	33 (14.3%)	0.013
Bradycardia	2 (2.2%)	4 (1.7%)	0.77
Pulmonary Outcomes
Intubated within 4 hours	2 (2.2%)	13 (5.6%)	0.193
Non-invasive positive pressure within 4 hours	1 (1.1%)	4 (1.7%)	0.689
Any ventilatory support within 4 hours	3 (3.3%)	17 (7.4%)	0.182
Intubated after 4 hours	2 (2.2%)	11 (4.8%)	0.298
Non-invasive positive pressure after four hours	2 (2.2%)	2 (0.9%)	0.327
Any ventilatory support after 4 hours	4 (4.4%)	13 (5.6%)	0.67
Central nervous system (CNS) Outcomes
Coma within 4 hours	24 (26.7%)	87 (37.7%)	0.063
Coma after 4 hours	12 (13.3%)	35 (15.2%)	0.682
Overall Outcomes
Death	1 (1.1%)	5 (2.16%)	0.528
Discharged from the ED	59 (65.6%)	147 (63.6%)	0.528
ICU Admissions	11 (12.2%)	39 (16.9%)	0.30
Miscellaneous
Length of Hospitalization (hrs.); median (IQR)	10 (5–28)	9 (5–36)	0.806
Total Naloxone Dose (mg)	3.68 (1.3–4.05)	2.8 (2–4.1)	0.448

Abbreviations: IQR = Interquartile range; DBP = Diastolic blood pressure; SBP = Systolic blood pressure; DBP = Diastolic blood pressure; HR = Heart rate; RR = Respiratory rate.

^*Percentage of entire cohort

Control = Xylazine negative.