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. 2021 Mar 25;19(2):355–364. doi: 10.5114/aoms/112525

Table II.

Survival outcomes of malignant pleural mesothelioma patients in multivariate analysis models

Parameter HR (95% CI)* P-value HR (95% CI)** P-value
Histopathology:
 Epithelioid Ref 0.001 Ref 0.001
 Others 3.70 (1.69–8.08) 4.51 (1.90–10.67)
Stage:
 I–II Ref 0.020 Ref 0.027
 III–IV 2.90 (1.18–7.10) 2.92 (1.13–7.59)
KPS:
 ≥ 80 Ref 0.040 Ref 0.001
 < 80 3.05 (1.05–8.83) 7.27 (2.22–23.79)
MDK:
 Low Ref 0.021 Ref 0.007
 High 2.91 (1.17–7.23) 3.89 (1.46–10.40)
SDC1:
 High Ref 0.009 Ref 0.053
 Low 3.47 (1.37-8.77) 2.77 (0.99-7.74)
HAS2:
 High Ref 0.005 Ref 0.008
 Low 2.72 (1.35–5.46) 2.77 (1.30–5.92)
SESN1:
 High Ref 0.014 Ref 0.014
 Low 3.67 (1.30-10.37) 4.0 (1.33-12.01)
LAMA4:
 High Ref 0.472
 Low 0.80 (0.44-1.46)
FBLN3:
 Low Ref 0.657
 High 0.78 (0.25–2.38)
*

Stage- and KPS-adjusted hazard ratios.

**

Multivariate hazard ratios.