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. 2023 Mar 27;27:15–57. doi: 10.1016/j.bioactmat.2023.03.006

Fig. 11.

Fig. 11

(A) Structural formula (a) of mussel foot proteins (Mfp-1). (b and c) The biomimicry of mussel-derived peptides (DOPA)4-G4-GRGDS and (DOPA)4-G4-YGFGG. (d) Schematic diagram of the surface dual-biomodification of Ti implants by using the mussel-derived peptides b and c [239]. (B) The assay of osteogenesis and mechanical stability in vivo: (a) Micro-CT 3D reconstructed images, (b) quantitative evaluations of the percentage bone volume (BV) among tissue volume (TV) (BV/TV), (c) histological images of Ti screws with toluidine blue stain, (d) average histomorphometric values of bone-implant contact (BIC), and (e) results of biomechanical pull-out testing. Implant NO. 1–4 refer to untreated (control), OGP-treated, RGD-treated, and OGP/RGD (3:1) dual-treated Ti screws, respectively [239]. Reprinted with permission from Ref. [239].