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. Author manuscript; available in PMC: 2023 Apr 5.
Published in final edited form as: Methods Mol Biol. 2022;2399:151–170. doi: 10.1007/978-1-0716-1831-8_7

Figure 5.

Figure 5

Correlation matrix of significantly changed metabolites in the heart from diabetic mice. Correlation matrix of the 43 metabolites responsible for treatment separations under G, GI, and GIP conditions in hearts from diabetic mice was obtained using MetaboAnalyst 3.0. The type (positive or negative) and strength (color intensity) of correlation are coded red and green, respectively, according to the bar on the right, and normalized between 1 and −1. Red arrows on the left denote strong positively correlated metabolites. Red on the diagonal correspond to correlation 1 for each metabolite with respect to itself. GSH, reduced glutathione; GSSG, oxidized glutathione; 3-HB, 3-hydroxybutyrate; SAH, S-adenosylhomocysteine

Reproduced (partially, only bottom panel) from Cortassa, Caceres, Tocchetti, Bernier, de Cabo, Paolocci, Sollott, and Aon (2020) J. Physiol. 598.7, 1393–1415.