Table 1.

eMERGE3 sites, population type, source of recruitment, whether RoR was required at the time of enrollment, primary planned method for RoR, and whether genetic counseling was embedded or offered in the RoR process

Group	Institution	Age Group	Source of Participants	RoR Required for Enrollment	Primary Planned Method for RoR	Genetic Counseling with RoRa
Group A	GE	Adult	Biorepository	Yes	Letter	Offered
	NU	Adult	Clinic, PGx biorepository	Yes	Phone	Offered
	VUMC	Adult	Clinic, PGx biorepository	Yes	Letter	Offered
Group B	CU	Adult	Community clinic, biorepository	No	Clinic, portal, letter, email	Embedded
	KPWA/UW	Adult	Biorepository	No	Clinic	Embedded
	MC	Adult	Biorepository	No	Clinic	Embedded
	MMC	Adult	Clinic	No	Clinic	Embedded
	PHC	Adult	Biorepository	No	Clinic	Embedded
	CCHMC	Pediatric	Biorepository, clinic, community	No	Clinic, portal	Embedded
	CHOP	Pediatric	Biorepository	No	Clinic	Embedded

The 3 institutions with adult populations (GE, NU, and VUMC) and genetic counseling offered in the RoR are listed first (Group A), followed by the 5 other adult institutions (CU, KPWA/UW, MC, MMC, PHC) and the 2 pediatric institutions (CCHMC and CHOP) (group B).

CCHMC, Cincinnati Children’s Hospital and Medical Center; CHOP, Children’s Hospital of Philadelphia; CU, Columbia University; eMERGE3, Electronic Medical Records and Genomics Phase III; GE, Geisinger; KPWA, Kaiser Permanente of Washington; MC, Mayo Clinic; MMC, Meharry Medical College; NU, Northwestern University; PGx, pharmacogenomics; PHC, Partners HealthCare; RoR, return of results; UW, University of Washington; VUMC, Vanderbilt University Medical Center.

^aCU, MC and CCHMC had multiple subpopulations.