Fig. 1. Schematic overview and workflow of the framework. The system description, a set of reversible reactions that describe how all species in the biomolecular system interact, is translated to a custom model by the model builder. After defining the experimental conditions using the config generator, experimental data can be used by the model solver in order to determine point estimates for any unknown parameters in the custom model. Subsequently, the custom model can be analysed by the framework. A number of diverse, extendible, and customizable methods were developed.
