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. 2023 Mar 22;14:1138078. doi: 10.3389/fendo.2023.1138078

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Copyright © 2023 Du, Xiang, Zhang, Yang, Zhao, Li, Zhou and Ma

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Vitamin D treatment ameliorate hepatic steatosis in NAFLD rats. (A) body weight, (B) energy intake, (C)liver weight, (D) liver coefficient, (E) H&E staining of liver tissues (400 × magnification) and Oil red O staining of liver tissue (400 × magnification). Four rats in each group were captured three views for evaluation of steatosis, lobular inflammation and balloon degeneration. Both scores are examined by an experienced pathologist who was unaware of the study. (F) Quantification of hepatic TG and (G) FFA in liver tissue. (H) NAFLD score and (I) Oil red O density of liver. Data were shown as the mean ± SEM. (n=8); ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.