Extended Data Fig. 5.

GPX4 works as a predictor of the response to cancer radiotherapy. (a) Kaplan–Meier analysis of overall survival for breast cancer patients who have undergone radiotherapy. (b–d) Kaplan–Meier analysis of overall survival for breast cancer patients (b), liver cancer patients (c), stomach cancer patients (d). (e–h) Cell-death measurements in MDA-MB-231 or MCF-7 subjected to the indicated treatments for 24 h or 28 h. MDA-MB-231; Tub, 4 μM; docetaxel, 1.25 μM; doxorubicin, 1.25 μM. MCF-7; Tub, 5 μM; docetaxel, 1.25 μM; doxorubicin, 1.25 μM. Data are the mean ± s.d.; n = 3 biologically independent experiments. Statistical analysis was performed using an unpaired two-tailed Student's t-test.