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. 2023 Mar 15;14(3):209–221. doi: 10.4239/wjd.v14.i3.209

Figure 3.

Figure 3

miR-124 targeted EZH2 and downregulated the expression of EZH2. A: miR-124 targeted EZH2 verified by a double luciferase reporter gene assay. B: The relative expression levels of EZH2 mRNA were upregulated by miR-124 inhibitor in high glucose-induced Min6 cells detected by real-time quantitative polymerase chain reaction; C: The relative expression of EZH2 protein was upregulated by miR-124 inhibitor in HG-induced Min6 cells detected by western blot. aP < 0.05, vs the mimic-NC group; bP < 0.05, vs BC group; cP < 0.05, vs the HG group. NC: Normal control; BC: Blank control; HG: High glucose.