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The role of WFS1 in Tau clearance in Alzheimer’s disease.
Schematic diagram outlining the potential mechanisms underlying the role of WFS1 in regulating tau clearance. CTSD: Cathepsin D; ER: endoplasmic reticulum; IRE1: inositol-requiring enzyme 1; pTau: phosphorylated tau; TFEB: transcription factor EB; UPR: unfolded protein response. Created with BioRender.com.
