TABLE 2.

Type of peripheral neuropathy associated with DNA repair disorders

DNA repair disorder	Sensory vs motor neuropathy	Axonal vs demyelinating neuropathy	Age of neuropathy onset
Xeroderma pigmentosum	Sensorimotor (XPA), sensory (XPD)	Axonal	Detected as early as 3 years for XPA, detected as early as adolescence for XPD 46
Trichothiodystrophy	Motor	Demyelinating	Detected as early as 6 months of age 56
Cockayne syndrome	Sensorimotor	Demyelinating	Severe slowing of conduction velocities observed at 2 years of age 71
Werner syndrome	Sensorimotor	Axonal and demyelinating	Neuropathy has been detected in the fourth decade of life and later, onset unclear 80 , 81 , 82
Ataxia telangiectasia	Sensorimotor	Axonal	Childhood onset with progression over time 131

Abbreviation: XP, xeroderma pigmentosum.