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. 2023 Apr 5;9(14):eadg6473. doi: 10.1126/sciadv.adg6473

Fig. 8. Self-association of FL-N and NA-liganded FL-N is mediated by LRS assembly.

Fig. 8.

SV experiments are carried out with three FL-N protein constructs (cyan): (A) the ancestral reference N-protein, (B) the mutant N:L222P that diminishes LRS folding and assembly, and (C) the double mutant N:L222P/R226P abolishing LRS assembly. Sedimentation coefficient distributions are shown in the presence of 10% TFE (blue), an excess of oligonucleotides T10 (green), and both 10% TFE and T10 (magenta).