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. 2023 Mar 14;39(4):btad130. doi: 10.1093/bioinformatics/btad130

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Three motifs identified by graph-theoretic methods for quality assurance. The red X represents a mapping (whether positive or negative) that was incorrectly curated and should be removed. (A) A prefix appearing twice in a triangle of positive mappings signifies that one node and all of its incident edges is incorrectly mapped. (B) A missing edge in a path of positive mappings with three nodes suggests the existence of a high confidence mapping. (C) A triangle with a negative mapping and two positive mappings implies one of the positive mappings is incorrect.