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. 2023 Apr 6;6:100200. doi: 10.1016/j.jtauto.2023.100200

Fig. 4.

Fig. 4

Glucocorticoids (GC) influence SARS-Cov2 memory T cell response in patients with SLE. A- Disease modifying therapies (DMT) repartition in the 47 SLE patients included in the study. B- Associations between DMT class usage and whole blood IGRA-S, IGRA-PHA, and IgG anti-Spike antibody (Ab) positivity. The positive thresholds of the tests are indicated. C- Whole blood IGRA-S results according to the usage of GC. D- Receiving operating characteristic (ROC) curve to establish the optimal level GC (Youden's index) to discriminate IGRA-S positive from IGRA-S negative SLE patients. Abbreviations: αBLys: anti-BLyS/BAFF monoclonal antibodies (mAb, belimumab); αCD20: anti-CD20 mAb (rituximab); αM: antimetabolite; HCQ: hydroxychloroquine; IGRA: interferon gamma release assay; PHA: phytohemagglutinin; S: spike; and p values < 0.05 are indicated when significant.